Top Manufacturers of Dermal Fillers

ACROSS

Across is a medical device manufacturing company that was founded in South Korea in 2009. They excel in research and development, production process, and high-quality control when creating products based on hyaluronic acid. They do so under the basic principle of life respect.

ALLERGAN

Allergan is one of the leading pharmaceutical companies that focuses on developing and producing medical aesthetic devices including facial injectables, body contouring, skincare, and more. They have many years of expertise in innovation and technologies used to provide aesthetic solutions to help people live a better life. Allergan is well-known for their dermal filler brand: Juvéderm. Juvederm is an injectable dermal filler for the face tissues, to iron out wrinkles and plump up the skin. Popularly used by patients who want to hide deep nasolabial folds.

ANIKA THERAPEUTICS

Anika Therapeutics is a global medical tech company that offers wound healing, pain management and tissue regeneration. They develop innovative medical solutions in order to help patients remain active in a safe and natural way. Anika Therapeutics is a manufactory that distributes a wide range of hyaluronic acid (HA) products specialized in therapeutic applications. HA is a natural component of the body that is vital to healthy tissue function. The brand only collaborates with industry leaders that deliver the newest therapeutic and advanced healthcare.

AQTIS

AQTIS Medical™ is a part of the leading Sinclair company that specializes in the research, development, and manufacturing of innovative injectable medical devices based on cutting-edge technology. With the focus on setting new standards within the bioresorbable medical aesthetic industry, AQTIS Medical™ has developed safe bioresorbable medical polymer and gel formulations, including the high-quality product line, Ellansé. The Ellansé family is a range of dermal fillers designed to correct wrinkles and other tissue imperfections. Sinclair is a global aesthetic company that provides aesthetic dermatology and collagen solutions targeting the clinical demand for effective, high-quality treatments.

BECTON DICKINSON

Becton Dickinson is a global medical technology company who develops, designs and sells medical equipment, instrument systems and reagents with a goal to help improve human health worldwide. BD was founded in 1897 with headquarter in Franklin Lakes, New Jersey, and operates in more than 50 countries worldwide. The company sells to healthcare institutions, life sciences researchers, clinical laboratories to the pharmaceutical industry and the general public. Becton Dickinson offers among others needle technologies, refillable syringes, safety and shielding systems. Furthermore, BD develops front-line needle technologies to combine an optimal needle point and cannula for drug requirements.

BIOSCIENCE

BioScience is a German family owned company from 2006 that produces medical devices based on hyaluronic acid. BioScience develops innovative injectable implants for treatments of different medical disciplines and is well known for their first aesthetic range called Hyacorp. Their aim is to provide the latest and safest technologies to ensure the safest solutions for their patients. BioScience is a recognized company using only raw materials from expert manufacturers and is today one of the world’s leading providers of hyaluronic acid gels.

BIOVENTUS

Founded in 2012 in their private headaquarter in Durham, NC. Bioventus has more than 700 employees worldwide. Bioventus are known for their efficiency, safety and innovative way of thinking. Their mission is to work with the health care community to help people resume and enjoy their active lives. Bioventus focuses their medical product development around two segments: Bioventus Surgical and Bioventus Active Healing Therapies. Bioventus Surgical is focused to advance surgical performance and science of orthobiologics. Bioventus Active Healing Therapies product range supports healing of bone fractures while treating the chronic pain associated with osteoarthritis. Bioventus product offering will expand in line with the market demand.

CAREGEN

Caregen was established in 2001 in Korea. Caregen is a global leader of research and marketing of Biomimetic Peptides and Growth Factors. Caregen are known for their commitment to innovation and technology, which gives them competitive advantage. Caregen is a dynamic, progressive and R&D based skin biology company. Caregen has a clear vision “To be a global leading company of growth factors and biomimetic peptides for cosmeceuticals and pharmaceuticals.”

CROMA

Croma-Pharma is an Austrian family-owned company based in Leobendorf that specializes in minimally invasive aesthetic medical devices with hyaluronic acid (HA). As one of the world’s leading experts in the field, Croma-Pharma offers a wide range of safe and effective beauty treatments with the long-lasting hyaluronic acid filler line, Saypha (formerly known as Princess filler). Croma-Pharma claims to have the most advanced HA filling line in the world based on its proprietary macro technology. Through intensive research and development, innovative cross-linking technology, and decades of process optimization and automation, Croma-Pharma ensures high quality, stability, and safety in its products.

DEXLEVO INC

Dexlevo is a Korean Medical Aesthetic company established in 2013 and are specialized in Biopolymer technology. The company is based on dermatology to achieve essential skincare and is innovative in trying to offer new and better values to their customers. Dexlevo has its own patented technology, CESABP (Collagen Enabled Solubilized Active and Biodegradable Polymer). They developed a fully solubilized biocompatible and biodegradable PCL (Polycaprolactone), which distributes efficiently into the skin. The technology effectively creates collagen synthesis on the entire skin. This results in, improvement of skin thickness, density, and elasticity without lumps or nodules. It is a complete innovation for fundamental anti-aging. Dexlevo has used this technology to develop the next-generation collagen stimulator, Gouri.

FILLMED LABORATORIES

Fillmed products are produced by the french aesthetic company Fillmed Laboratories. Fillmed offers a broad range of facial rejuvenation treatments like anti-aging, mesotherapy, and medical injection fillers to correct signs of aging and improve skin quality. The range includes an exclusive collection of hyaluronic acid Art Filler to eliminate wrinkles and create volume, a unique NTCF injectable solution with high HA-concentration NTCF 135HA to improve skin quality, and further mesotherapy products (M-HA) to improve hydration and rejuvenate the skin. The Fillmed brand provides unique formulas of hyaluronic acid and high-performance active ingredients to help address the common signs of aging skin including hydration, radiance, wrinkles, and skin tone.

GALDERMA

Galderma is a global dermatology company partnering with healthcare professionals to provide innovative medical solutions to patients with skin health needs. The Restylane beauty line offers a solution for a wide range of lines surfacing across the face, whether they are worry lines, glabella lines, perioral lines and many more. Many Restylane products contain lidocaine to act as an anaesthetic- the pain free solution. Furthermore, Galderma offers the unique PLLC collagen stimulator, Sculptra, which is designed to promote collagen production and restore the skin’s inner structure and volume.

GENZYME

Genzyme (Sanofi) is an international business of care, specialized on rare diseases, oncology, multiple sclerosis and immunology. The company works on debilitating and complex conditions, that can be challenging to diagnose. Sanofi Genzyme is providing new therapies and give hope to clients and their families around the world. Genzyme is specialized in medicine relating to lysosomal storage diseases, renal disease, orthopedics, transplant and immune diseases, oncology, genetics and diagnostics.

GENOSS

Genoss is a South Korean manufacturing company of medical devices founded in 2004. Genoss aims to deliver treatment solutions and promotes the well-being of its customers and patients. Genoss is the manufacturer of aesthetic and dental medicine and devices. Among these products is the Monalisa dermal filler line where the base of the fillers is hyaluronic acid. The raw material of HA is produced in Genoss’ facilities. Genoss has a strict triple-check quality procedure to control the manufacturing system. This makes the Monalisa product portfolio a very safe dermal filler line that complies with international regulations including KGMP, ISO 13485, and ISO 9001. Further, the Monalisa product line is CE-certified.

IBSA

The IBSA Group is founded by a group of Swiss biologists in 1945, IBSA – Institute Biochimique SA has gained a unique experience in pharmaceutical research and technology. IBSA is a one of the leading pharmaceutical companies in developing medical devices based on hyaluronic acid and raw materials. IBSA DERMA is the manufacturer of Profhilo, a new innovative solution for skin rejuvenation - Read more about Profhilo & Viscoderm.

JETEMA

Jetema is a Korean beauty biopharmaceutical company that develops and researches cosmetic medicines. Jetema was founded in 1999 and produces botulinum toxin, threads, and hyaluronic acid fillers. Jetema is a company with big ambitions and strives to be a market leader within dermal fillers and botulinum toxins on the Asian market. Besides producing aesthetic medicine, Jetema also develops equipment and medicine devices.

LABORATORIO INNOAESTHETICS

Laboratorio Innoaesthetics S.L is a worldwide-recognized company and laboratory in the aesthetic medicine and dermo-cosmetic industries that provide dermatological solutions to treat any kind of changes in skin quality. The company has more than a century of experience in developing pharmaceutical formulas to improve skin conditions like hyperpigmentation, acne and dark spots as well as developing transdermal solutions for cases with cellulite, sagging skin and loss of skin firmness. Laboratorio Innoaesthetics S.L are well known for their two leading brands: Innoaesthetics and MeLine for professionals and end-users. AN EXTENSIVE PRODUCT RANGE OF HIGH-QUALITY SOLUTIONS: Laboratorio Innoaesthetics’ products are formulated with innovative ingredients that work in perfect synergy to perform the best results and meet the customers’ expectations while maintaining healthy and beautiful skin. MeLine is a line of aesthetic products specifically designed to treat hyperpigmentation, whereas Innoaesthetics offers a broad portfolio of transdermal solutions for mesotherapy.

LOVE COSMEDICAL

Love Cosmedical is a young Italian company that offers revolutionary fat dissolving treatments as a result of professional know-how and cutting-edge technologies. The company has great expertise in cosmetic medicine and high-quality products leaving great results while maintaining a high level of safety. Love Cosmedical Neofound is a bio revitalizer that holds active ingredients with the properties of anti-wrinkle smoothing effects, skin cell rejuvenation, stimulation of collagen and skin tone enhancement.

MARLLOR BIOMEDICAL

Marllor Biomedical designs, develops and markets medical device technology and provides a technical contribution to the scientific leading non-surgical procedures in medicine and cosmetic dermatology. Marllor Biomedical produces the brand Alidya which is the first injectable solution for treating cellulite based on amino acids and other ingredients.

MATEXLAB

Matexlab produces highly innovative ranges of dermal fillers and cosmeceuticals and is headquartered in Lugano. The company has great expertise in the areas of: injectables, such as dermal fillers and biorevitalizers; anti-aging and lenitive creams; tissue regeneration systems and healing serums with sterile masks. Neauvia Organic is the main Matexlab brand and is the world’s first line of dermal fillers so close to nature. Neauvia Organic combines hyaluronic acid with a unique PEG-cross-linked technology, which makes each filler specific for different indications and injections.

MD SKIN SOLUTIONS

MD Skin Solutions is based in Luxemborg and is a European ISO 13485 certified laboratory specialized in developing anti-aging treatments and solutions. MD Skin Solutions have expertise in bio-revitalisation and focus on innovation and safety. MD Skin Solutions is well known for their Pluryal range, which is a new generation of hyaluronic acid dermal fillers and booster that dramatically reduce the signs of skin aging and provide lasting natural results.

Medixa

Medixa srl was founded in 2008 and is specialized in producing certified medical products and equipment for the aesthetic business. Based on many years of research and collaboration with medical professionals Medixa products are created to improve the aesthetic industry. All products from Medixa are certified and the production is regulated by the ISO 13485 standard.

MERZ

Merz is a global, family-owned aesthetics and neurotoxin company that produces dermatology products. Merz is driven by the opportunity to help people look better, feel better and live better, and provides a unique and well-balanced product portfolio designed to deliver personalized, natural looking outcomes for face and body. In addition, their product portfolio offers a comprehensive line of dermal fillers, a professional skincare range, a skin-tightening and lifting device and a revolutionary cellulite treatment. One of their most significant products are Belotero fillers, an extended range of hyaluronic acid fillers for smoothing and filling wrinkles as well as lip augmentation. Our other brands from Merz are Etermis and Radiesse.

MESOESTETIC PHARMA GROUP

Since 1985, Mesoestetic Pharma Group has been a leading pharmaceutical laboratory in the field of dermatology and aesthetic medicine. The Spanish laboratory is well known for its innovative skincare solutions and treatments including antiaging therapies and depigmenting treatments. Their aesthetic solutions are characterized by a high degree of safety and effectiveness that comply with national and international standards. Mesoestetic Pharma Group manufactures cosmeceutical, nutraceuticals, class III intradermal administration medical devices, and more. The pharmaceutical company is especially recognized for its popular brand: Mesoestetic, which is considered as one of the world's leading treatment for hyperpigmentation and melasma thanks to their cosmelan line.

OBVIELINE

ObvieLine Laboratorie is a French company created in 2005 that specializes in the research, development, manufacturing and distribution of hyaluronic acid (HA) dermal fillers. Laboratoire ObvieLine received their ISO 13485 certification in 2007 and was acquired by Sinclair Pharma in 2015. ObvieLine has developed Perfectha, a complete range of hyaluronic acid fillers ideal for wrinkles correction, facial contouring and volume restoration. All Perfectha products have received CE markings to ensure patients optimal safety. Perfectha is the perfect filler, because of its unique cross-linking technology and its long-lasting results.

OREON LIFE SCIENCE

Oreon Life Science is an international Korean company specialized in anti-aging and medical aesthetics founded in 2000. Oreon has a wide product range including fillers, threads, cosmeceuticals and dermatologic products. They are especially focused on their varied range of Rainbow Threads, which they are consistently improving to ensure the best quality products to customers worldwide. The Rainbow thread is a non-surgical anti-aging treatment for lifting and shaping facial contours. Oreon is highly focused on being innovative and safe by using only high-quality materials and advanced manufacturing technologies that ensure the finest quality standards. In our online shop you can find a wide range of Rainbow Threads.

PROFESSIONAL DERMA

Professional Derma, founded in 2006, is a Swiss well-established biotechnology company focused on developing innovative medical devices and revolutionary skin bio-revitalizing products. Professional Derma has many years of expertise in manufacturing aesthetic medicine with the use of amino acids and their revitalizing properties. One of the main brands is Jalupro, a range of skin rejuvenating products designed to protect and improve the skin.

PROLLENIUM

The Revanesse family of products is manufactured in Aurora, Ontario by Prollenium Medical Technologies Inc. Prollenium focuses its attention on the research, production, marketing, and sales of novel biomaterials that can be used for tissue reconstruction. Prollenium is highly committed to the research and development of safe and effective products.

REVITACARE PRODUCTS

Revitacare is a French laboratory, specialized in research, design, and manufacturing of implants and products dedicated to cosmetology and aesthetic medicine used in the prevention and correction of the skin aging effects, and the treatment of hair problems. Revitacare product line is rich but one of their most popular brands are Cytocare. Cytocare is a range of resorbable implants composed of hyaluronic acid and rejuvenating complex ideal for treating fine lines, wrinkles, and dehydrated skin.

PROMOITALIA

Promoitalia is a research and manufacturing company within medical aesthetics. The company was founded in Italy in 1994 and has since grown into a worldwide company with more than 12 offices around the world. The company is the developer and manufacturer of the well-known dermal filler brand Nucleofill but does also have food supplements and slimming devices within its product portfolio. Promoitalia is a modern manufacturing company that believes in the mission of overall beauty for all.

Sculptra

Sculptra is a popular anti-aging treatment used to treat wrinkles and sagging skin by stimulating the skin’s collagen production thanks to its unique formula of Poly-L-Lactic Acid (PLLA). Unlike traditional hyaluronic acid fillers that work as volumizers, Sculptra is a biostimulator that does not provide filling actions. Instead, Sculptra has the ability to stimulate the tissue through collagen-formation, which leads to a tightening of the skin while rebuilding lost volume for up to 24 months. This makes the collagen stimulator a great alternative to hyaluronic acid injectables ideal to use for treating smile lines, marionette lines, and chin wrinkles.

SOFT MEDICAL AESTHETICS

Founded in 2009, Soft Medical Aesthetics designs and manufactures innovative cannulas intended for healthcare professionals. Soft medical Aesthetic offers a real innovation in the field of aesthetics with a revolutionary range of micro-cannulas, needles and devices known under the SoftFil brand. The range is based on the concept of "Soft Filling Technique", a standardized injection method, dedicated to filling products.

SOLTA MEDICAL

Solta Medical is a global leader in the aesthetic industry and has for more than a decade been developing innovative treatment technologies to provide effective aesthetic care options for consumers and physicians alike. Solta Medicals' portfolio of products includes Thermage – The #1 provider of skin tightening treatments. The Thermage System is a non-invasive radiofrequency therapy that smooths, tightens, and contour skin for an overall younger-looking appearance.

TEOXANE

Teosyal® offers a large portfolio of dermal fillers customized for treating different areas and indications, such as smooth out wrinkles, reduce signs of aging and restore lost volume. The products consist of biodegradable hyaluronic acid, which increase the skin’s hydration and softness, and leaves the skin moisturized, plumped and healthy. Teosyal® fillers are designed to treat the following areas: upper face, mid face, lower face, neck and neckline. Furthermore, the Teosyal Puresense and RHA products contain lidocaine for a more comfortable injection.

VIVACY PRODUCTS

Laboratories Vivacy is a French manufacturer specializing in the design, production and distribution of high quality injectable medical devices for use in the field of Anti-ageing, especially in Medical Aesthetics and Viscosupplementation. Click on the links and read more about Desirial and Stylage from Vivacy.

TSK

TSK Laboratory manufactures premium quality needles and cannulas for the global aesthetic market. TSK is well-known for its wide range of specialty needles for filler, mesotherapy, and botulinum toxin injections. TSK strives to make injections perfect and has a long successful history in the development and manufacturing of needles and medical devices, which has resulted in multiple patents for both materials and needle designs. TSK deliver new solutions to the aesthetic branch, that improve the clinical outcome while simultaneously improving patient safety and comfort.

WIQOMED

WiQomed is an Italian-based company founded in 1994 and build on a foundation of research and passion. The company specializes in derma cosmetic products and medical devices that are well researched and qualified in the technological and scientific fields. The company successfully developed the product line PRX. Both product lines are designed to maintain healthy skin for all skin types with the key factors: protection, prevention, and stimulation.

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